Regional variations in overall cancer rates may mask important differences in composition of cancers. The most frequently diagnosed cancers by sex vary considerably across country. The most commonly diagnosed cancer among men is lung cancer in most parts of Eastern Europe and Asia; prostate cancer in North America, Australia, Western and Northern Europe, and South America; liver cancer in parts of West Africa; Kaposi sarcoma in central parts of Africa; esophagus in East Africa; and bladder cancer in Egypt. Among women, the most frequently diagnosed cancer is breast cancer in most parts of the world, including Australia, Western Asia, North Africa, North America, and parts of South America; cervical cancer in Central America, parts of South America, Sub-Saharan Africa, and India; liver cancer in Mongolia and Vietnam; and lung cancer in China and North Korea.